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Case Studies

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Tackling HIV prevention with holistic insights and interventions

Tackling HIV prevention with holistic insights and interventions

Tackling HIV prevention with holistic insights and interventions

How the Bill & Melinda Gates Foundation addressed social, economic, and emotional drivers

How the Bill & Melinda Gates Foundation addressed social, economic, and emotional drivers

8x

higher HIV risk in women

3x3

empowerment framework

120

participants engaged

2

countries in focus

The challenge

Understanding complex social factors fuelling HIV vulnerability

Adolescent girls and young women in sub-Saharan Africa face disproportionately high HIV risk driven by multiple intertwined factors: economic dependency, social norms, relationship dynamics, and limited prevention uptake. Traditional single-focus interventions struggle to address this nuanced, multifaceted challenge.

Key challenges

  • Lack of context-specific, holistic frameworks

  • Complex motivations behind risky relationships

  • Limited influence of standard prevention programs

  • Intertwined emotional, social and economic pressures

The solution

Crafting holistic frameworks for targeted interventions

Multidimensional research

Qualitative & quantitative

Scenario-based EthnoLab™

Contextualized insights

Tailored frameworks

3x3 empowerment model

5-step relationship journey

Segmentation by motivations

Implementation approach

1

Local engagement

  • Cultural sensitivity

  • Tanzania & South Africa

  • Community interviews

2

Behavioral mapping

  • Self-agency factors

  • Relationship priorities

  • Identifying motivations

3

Iterative refinement

  • Feedback loops

  • Evolving prototypes

  • Partner collaboration

The impact

Empowering person-centered HIV prevention strategies

Deeper understanding

8x

HIV risk for women

  • Complex social drivers

  • Beyond material incentives

  • Tailoring informed interventions

Actionable frameworks

3x3

empowerment pillars

  • Bespoke program design

  • Sustainable skill building

  • Emotional, social, economic

Contextual relevance

5 step

relationship journey

  • Meeting women’s real goals

  • Aligning prevention & desires

  • Culturally adapted approaches

Looking ahead

Scalable application

  • Adapting novel frameworks regionally

Refined interventions

  • Growing segment-specific programs

Continuous insight

  • Integrating evolving community feedback